PF-998425 8963 4 mM PD0325901 and 1

4 mM PD0325901 and 1 mM CHIR99021 in DMSO

In contrast

CAS Number: 958843-91-9

these data confirm the utility of GF120918A as a tool P-glycoprotein inhibitor in preclinical species and offer additional guidance on preclinical dose regimens likely to produce P-glycoprotein-mediated effects

PF-998425 8963 4 mM PD0325901 and 1PF 998425 is a potent, selective nonsteroidal androgen receptor (AR) antagonist with an IC50 of 37 nM and 43 nM in AR binding and cellular assays, respectively. PF 998425 has low activity on common receptors and enzymes, such as progesterone receptor. PF 998425 can be used for sebum control and androgenetic alopecia research. Product information CAS Number: 1076225 27 8 Molecular Weight: 269. 26 Formula: C14H14F3NO Chemical Name: 4 [(1R,2R) 2