Pay in 4 interest-free payments of $25.00 Learn more
Ships within 48 hours · Estimated delivery Jul 27 - Aug 1
%F of 101 by oral administration of 4 mg/kg in mouse
and myelodysplastic syndrome
19 149 PMID: 32127666
Formula: C8H11NO
Volasertib trihydrochloride - CAS# 946161-17-7 bradine Hydrochloride %F of 101 by oralVolasertib (BI 6727) trihydrochloride is an orally active, highly potent and ATP competitive Polo like kinase 1 (PLK1) inhibitor with an IC50 of 0. 87 nM. Volasertib trihydrochloride inhibits PLK2 and PLK3 with IC50s of 5 and 56 nM, respectively. Volasertib trihydrochloride induces mitotic arrest and apoptosis. Volasertib trihydrochloride, a dihydropteridinone derivative, shows marked antitumor activity in multiple cancer models. Product information
US$ 11.99
US$ 17.99
US$ 30.00
US$ 18.99
US$ 30.99