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ZM-447439 selectively inhibits recombinant human Aurora A and B with IC50 values of 110 and 130 nM
Epub 2019 Feb 28
Chaperone-Mediated Regulation of Choline Acetyltransferase Protein Stability and Activity by HSC/HSP70
Formula: C21H18FN5O
BSJ-03-204 4352) ZM-447439 selectively inhibits recombinant humanBSJ 03 204 is a potent and selective Palbociclib based CDK4 6 dual degrader (PROTAC), with IC50s of 26. 9 nM and 10. 4 nM for CDK4 D1 and CDK6 D1, respectively. BSJ 03 204 does not induce IKZF1 3 degradation and has anti cancer activity. Product information CAS Number: 2349356 09 6 Molecular Weight: 832. 90 Formula: C43H48N10O8 Chemical Name: N (4 {4 [6 ({6 acetyl 8 cyclopentyl 5 methyl 7 oxo 7H, 8H pyrido[2, 3 d]pyrimidin 2 yl}amino)pyridin 3
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