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The incubation of Chlorotrianisene with rat liver microsomes and NADPH in the presence of rat uteri
Formula: C22H44O7S
(2013) J Am Chem Soc
Schwendeman SP
PROTAC Mcl1 degrader-1 exetil) The incubation of Chlorotrianisene withPROTAC Mcl1 degrader 1 (compound C3), a proteolysis targeting chimera (PROTAC), is a potently and selectively Mcl 1 inhibitor with an IC50 of 0. 78 M. PROTAC Mcl1 degrader 1 induces the ubiquitination and proteasomal degradation of Mcl 1 by introducing the E3 ligase cereblon (CRBN) binding ligand pomalidomide to Mcl 1 inhibitor S1 6 with M range affinity. Product information CAS Number: 2163793 38 0 Molecular Weight: 909. 84 Formula: C45H45BrN6O8S
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