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InChi: InChI=1S/C22H21N3O2/c1-22(2)12-13-9-19(26-3)20(27-4)10-14(13)18-11-17-21(25(18)22)24-16-8-6-5-7-15(16)23-17/h5-11H
1007/s00586-014-3675-2
Probe Reports from the NIH Molecular Libra
Formula: C20H30N2O5
M-110 0192 InChi: InChI=1S/C22H21N3O2/c1-22(2)12-13-9-19(26-3)20(27-4)10-14(13)18-11-17-21(25(18)22)24-16-8-6-5-7-15(16)23-17/h5-11HM 110 is a inhibitor of protein arginine N methyltransferases (PRMTs). It is also a highly isoform selective, cell permeable and potent ATP competitive inhibitor of the PIM kinase family that prefers PIM 3, shown to inhibit the proliferation of prostate cancer cell lines with IC50s between 0. 6 to 0. 9 M, with no activity on normal human peripheral blood mononuclear cells up to 40 M. Product information CAS Number: 1395048 49 3 Molecular Weight: 445.
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