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187:111952
40(6):3071-3080
InChi: InChI=1S/C37H34ClN5O4S/c1-37(2
HY50736 is an USP7/USP8 inhibitor
CMLD-2 - CAS# 958843-91-9 Demethylase 187:111952CMLD 2, an inhibitor of HuR ARE interaction, competitively binds HuR protein disrupting its interaction with adenine uridine rich elements (ARE) containing mRNAs (Ki=350 nM). CMLD 2 induces apoptosis exhibits antitumor activity in different cancer cells as colon, pancreatic, thyroid and lung cancer cell lines. Hu antigen R (HuR) is an RNA binding protein, can regulate target mRNAs stability and translation. Product information CAS Number: 958843 91 9