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LY2409881 trihydrochloride Catalog No.:M8341-10 InChiKey: RHUJMHOIQBDFQR-UHFFFAOYSA-N

SKU: 48013309969

4.2
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Description

InChiKey: RHUJMHOIQBDFQR-UHFFFAOYSA-N

PD-161570 suppresses constitutive phosphorylation of the FGF-1 receptor in both human ovarian carcinoma cells (A121(p)) and Sf9 insect cells overexpressing the human FGF-1 receptor and blocked the growth of A121(p) cells in culture

or DBP(diastolic blood pressure)

175(1-3):1-7

LY2409881 trihydrochloride Catalog No.:M8341-10 InChiKey: RHUJMHOIQBDFQR-UHFFFAOYSA-NLY2409881 is a potent and selective IKK2 inhibitor. LY2409881 potently synergizes with histone deacetylase inhibitors in preclinical models of lymphoma through the downregulation of NF B. LY2409881 inhibited constitutively activated NF B, and caused concentration and time dependent growth inhibition and apoptosis in lymphoma cells. LY2409881 suppressed the activity of the NF B subunit p65 in lymphoma cells treated by the HDAC inhibitor romidepsin,

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