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3-dihydro-1H-isoindol-4-yl}acetamide
a study based on PKC-ι and PKC-ζ specific inhibitors
and MIP-1β was also suppresses
H-1152 2HCl
BPN-15606 besylate xin G2 3-dihydro-1H-isoindol-4-yl}acetamideBPN 15606 besylate is a highly potent, orally active secretase modulator (GSM), attenuates the production of A42 and A40 by SHSY5Y neuroblastoma cells with IC50 values of 7 nM and 17nM, respectively. BPN 15606 besylate lowers A42 and A40 levels in the central nervous system of rats and mice. BPN 15606 besylate has acceptable PK PD properties, including bioavailability, half life, and clearance. Product information Molecular Weight: 576. 64 Formula:
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