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20S)-2-((1H-indol-3-yl)methyl)-8-(3-amino-3-oxopropyl)-11-(4-aminobutyl)-17-benzyl-20-((2S
with a Kd of 79 nM
71(6):1049-51
49)/b21-20+/t30-
Ponesimod bersonine hydrochloride 20S)-2-((1H-indol-3-yl)methyl)-8-(3-amino-3-oxopropyl)-11-(4-aminobutyl)-17-benzyl-20-((2SPonesimod (ACT 128800) is a potent, selective and orally active agonist of S1P1, with an IC50 of 6 nM in a radioligand binding assay. Ponesimod activates S1P1 mediated signal transduction with high potency (EC50=5. 7 nM). Ponesimod can protect against lymphocyte mediated tissue inflammation. Product information CAS Number: 854107 55 4 Molecular Weight: 460. 97 Formula: C23H25ClN2O4S Chemical Name: (2E,5Z) 5 ({3 chloro 4 [(2S) 2,3
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