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Formula: C18H19ClN6O2S
particularly for the p53R175 mutant
Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure
Heclin does not block E2 binding but causes a conformational change that results in oxidation of the active site Cys
GSK2879552 dihydrochloride - LSD1 Inhibitor. CAS# 1902123-72-1 size:10mg solid Formula: C18H19ClN6O2SGSK2879552 dihydrochloride, CAS No. 1902123 72 1, is a highly potent, selective and orally bioavailable irreversible inhibitor of Lysine Specific Demethylase 1 (LSD1). It is highly selective over related enzymes such as MAO A B. A proliferation screen of cell lines representing a number of tumor types indicated that small cell lung carcinoma (SCLC) is sensitive to GSK2879552s inhibition. It increases H3K4 methylation selectively at genomic regions
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