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with Kis of both 1 nM
Epub 2014 May 30
Epub 2010 Jan 29
Formula: C17H27Cl2N3O
O-Methylviridicatin R-VIVIT TFA with Kis of both 1IC50: 2. 5 M: inhibits virus production in OM 10. 1 cells (HL 60 promyelocytes infected with HIV 1) treated with TNF . 5 M: blocks activation of the HIV long terminal repeat by TNF in HeLa cells O Methylviridicatin, a natural derivative of the alkaloid mycotoxin viridicatin, is produced by several species in the genus, Penicillium. It is demonstrated that O Methylviridicatin, as an inhibitor, blocks the tumor necrosis factor alpha (TNF) induced
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